Could the solution to everlasting youth truly be as easy as taking a daily ‘miracle’ pill?

That’s the recommendation from professionals regarding a specific supplement found in pharmacies and stores throughout the nation.

Regarding Nicotinamide Mononucleotide, also referred to as NMN supplements, medical professionals have stated that it “can reduce your age by several years.”

Priced as low as £34 for 30 capsules—equivalent to £1 per day—at stores such as Boots, supporters argue the supplement may also aid in increasing energy levels, boosting metabolic rate, and supporting cognitive function.

Some studies have also indicated it might reduce the age of specific cells and muscles by several decades.

Infamous biohacker and longevity entrepreneur Bryan Johnson—who is 47 years old but has the physique of a man in his 30salso incorporates NMN supplements into his anti-aging regimen.

Other specialists, nevertheless, recommended caution regarding the results, stating that the majority of studies conducted so far have included either mice or brief human trials. They emphasize that additional research needs to be carried out first to confirm that administering the higher doses used on mice is safe for humans.

Within the body, NMN is transformed into a similar compound known as nicotinamide adenine dinucleotide (NAD), which exists in all cells of living organisms and is crucial for survival.

NAD plays a vital role in activating seven distinct genes within our body that control the aging process.

However, our NAD levels decrease by approximately 50 percent as we grow older, disabling the body’s protections against aging and age-related conditions likecancer, diabetes, cardiovascular disease and Alzheimer’s.

NMN supplements, in principle, counteract the impacts of aging and help maintain NAD levels as they decrease.

Dr. Paul Banwell, a plastic and cosmetic surgeon based in Sussex and an expert in longevity, stated to the Daily Mail: ‘NMN and NAD supplements have the potential to reduce your biological age.’

That’s why I would strongly suggest incorporating NAD supplements into your initial biohacking and health regimen.

‘I personally take ARTIS LondonRegenerative Complex, which includes sirtuin activators that work together to enhance NAD levels.

Decreased amounts of NAD in the body may result in impaired DNA repair, lower energy levels, and metabolic issues, potentially leading to additional problems like insulin resistance and elevated blood pressure, as well as an increased risk of age-related conditions.

Dr. Sabine Donnai, a general practitioner and founder of the private London health clinic Viavi, said to the Daily Mail: ‘No other substance is as effective as NMN in supporting your cells to operate at their best.’

This implies that pain, inflammation, and fatigue decrease, while mental clarity, endurance, recovery, energy, and a sense of youthfulness improve when NAD is enhanced through NMN.

More significantly, it encourages cellular repair and renewal, thereby enhancing lifespan.

Certainly, Dr. David Sinclair, a genetics professor at Harvard Medical School and co-author of Lifespan: Why We Age—and Why We Don’t Have To, has dedicated two decades to researching ways to “cure” aging and also thinks NMN holds the most promise as a solution.

In a particular study, he discovered that after only a week of consuming NMN mixed into their drinking water, the cells of aged mice became virtually identical to those of younger mice.

Their muscles appeared and functioned like those of a young mouse, as well.

In human terms, it was like a 60-year-old’s cells and muscles changing into those of a 20-year-old, he explained.

As stated in the team’s research published in the international journal Science, the mice experienced no harmful side effects.

However, he warned that what often works effectively in laboratory mice does not always apply to the more complicated systems of humans.

Dr. Cathy Slack, an associate professor at the University of Warwick who focuses on the biology of aging, also cautioned that further studies are required before scientists can definitively establish NMN’s anti-aging effects.

“Much of the research done up to now has been performed on cells in a lab or in animal studies,” she stated.

Clinical trials need to initially examine the safety of administering the substance to humans over extended periods, using relatively high doses similar to those given to mice.

Studies typically administer mice doses of NMN ranging from 500 to 1000mg daily.

NMN supplements available at Boots, for example, come in 250mg doses and are recommended for individuals 25 years old and older.

Indeed, one 2021 trial including 48 young and middle-aged athletes, it was discovered that consuming the supplement in large amounts over only six weeks enhanced cardiovascular endurance in runners.

A further 12-week study featured in the journalNutrientsIn 2022, a small amount of NMN enhanced muscle reaction and sleepiness in elderly individuals.

A third study, a 2023 review examining the safety and possible anti-aging benefits of NMN supplements in current human clinical trials, found that although the supplement is gaining significant popularity, most prior research on its effects has been conducted on cellular or animal models.

Writing in the journal Advances in Nutrition, Chinese researchers noted that 12 human clinical trials examining NMN supplementation were being conducted.

Evaluating their development, they stated that although oral NMN consumption is typically safe, and although only a small number of markers have been examined, the findings do indicate possible anti-aging benefits.

However, “more extensive, larger, and better-structured human studies are required to examine the safe dose, acceptance, and occurrence of NMN administration.”

Dr. Leonard Josipovic, a plastic surgeon and expert in supplements, also mentioned to the Daily Mail: “Individuals who consume NMN frequently say they experience increased energy levels, improved mental clarity, and reduced tiredness.”

Early research also suggests potential advantages for heart health, muscle stamina, insulin responsiveness, and resistance to oxidative stress.

In a nutshell, although it’s not a “eternally youthful” remedy, NMN might serve as a useful aid in preserving cellular health and energy levels as we grow older.

Currently, specialists recommend that the most effective actions individuals can maintain to slow down aging are the traditional ones—adequate sleep, regular physical activity, and a balanced, vegetable-filled diet.

Dr. Slack noted: “We typically obtain it through our diet, including foods such as avocados, dairy products, and red meat. Our cells can also generate NMN indirectly from vitamin B3.”

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